Linguatula serrata is the causative parasite of Linguatulosis, a disease that not only produces economic losses in
cattle but also represents a public health risk due to its zoonotic nature. This study aimed to microscopically characterise the compatible
lesions produced by this parasite in bovine liver collected at a slaughterhouse in the city of Curicó, Chile. Histologic compatible
lesions with Linguatulosis were observed in 18 out of 269 livers. Furthermore, nymphs were visualised in 3 cases, allowing an
etiologic diagnosis. Microscopic lesions containing nymphs demonstrated two patterns of inflammatory reactions, one pattern with
a predominance of eosinophils, accompanied by lymphocytes and some macrophages, and another pattern with a predominance of
lymphocytes and plasma cells with some macrophages. A microscopic characterisation was performed in compatible lesions without
nymphs (n=15), defining 4 types of granulomas attributable to visceral Linguatulosis, according to the presence and features of cells
at the centre of the lesion, the presence of presumably degenerated nymphal structures, location of inflammatory infiltrate, as well as
location and amount of surrounding fibrous tissue. These lesions can concede a presumptive microscopic diagnosis. Also, different
microscopic features of granulomas compatible with Linguatulosis analysed in this study suggest a temporal evolution of the lesions.
The description of lesions generates a better understanding of the host-parasite interaction of this agent which has importance in both
animal productivity and public health.